Scientists at UCLA have created a new synthetic metabolic pathway for hydrolyzing glucose that could lead to a 50% increase in the production of biofuels! Nearly all organisms use glycolysis to convert 4 of the 6 carbon atoms in glucose into 2-carbon molecules of acetyl-CoA. Acetyl-CoA is used to make biofuels (ethanol & butanol), fatty acids, amino acids, and pharmaceutical products. The problem is that the 2 remaining carbon atoms in glucose are lost as carbon dioxide gas and this is seen as a major inefficiency in the biorefining process.