This video from 3 Minutes of Fun shows eosinophil granulocytes chemotaxing to an IgE-opsonized multicellular parasite. During a normal immune response to helminths, eosinophils degranulate and release cationic granule proteins (major basic protein [MBP], eosinophil cationic protein [ECP], eosinophil peroxidase [EPO], and eosinophil-derived neurotoxin [EDN]) to destroy pathogens too large to be endocytosed by phagocytes. They also induce mast cells and basophil granulocytes to degranulate, thus releasing histamine and proteolytic enzymes.