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Tuesday, February 17, 2015

Watch Eosinophils Attack a Parasite

This video from 3 Minutes of Fun shows eosinophil granulocytes chemotaxing to an IgE-opsonized multicellular parasite. During a normal immune response to helminths, eosinophils degranulate and release cationic granule proteins (major basic protein [MBP], eosinophil cationic protein [ECP], eosinophil peroxidase [EPO], and eosinophil-derived neurotoxin [EDN]) to destroy pathogens too large to be endocytosed by phagocytes. They also induce mast cells and basophil granulocytes to degranulate, thus releasing histamine and proteolytic enzymes. 



 Eosinophil image from Blausen.com staff. Blausen gallery 2014. Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018762.

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1 comment:

  1. creative enzymesSeptember 22, 2018 at 10:01 AM

    Eosinophil peroxidase is an enzyme found within the eosinophil granulocytes, innate immune cells of humans and mammals. eosinophil peroxidase

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