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Monday, September 24, 2012

First gene therapy successful against aging-associated decline: Mouse lifespan extended up to 24% with a single treatment


Inducing cells to express telomerase, the enzyme which extends the telomeres (ends of linear chromosomes) also extends the lifespan of mice. This study shows that life extension is actually a doable thing and could improve the health span of us!

Many studies have shown that you can increase lifespan of many species, including mammals, by acting on specific genes, but that usually involves altering genes in embryos. Not something to be done with humans.

Researchers at the Spanish National Cancer Research Centre have shown that the mouse lifespan can be extended by the application in adults of a single treatment acting directly on genes. And they have done so using gene therapy, a strategy never before employed to combat aging.The therapy has been found to be safe and effective in mice.

Read the Science Daily article HERE.

Visit the Spanish National Cancer Research Centre website HERE.

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